The information provided by LCR Health is based purely on documented research. Below you can read the verified research behind Active Stem™.

All research listed below have citations or actual links to clinical studies, so you can verify the information yourself.

Improved Cognitive Function

• Carnosine has been shown in clinical trials to be a powerful factor in protecting against neurodegeneration.

Enhanced Joint and Muscle Strength

• Leucine has been shown to stimulate protein synthesis in muscles.

Increased Longevity

• Carnosine has been shown to not only extend the lifespan of mice in laboratory trials, but also slow the aging of human cells.


Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging


Raising NAD+ levels in old mice reverses metabolic dysfunction and restores mitochondrial function to that of a young mouse.

Trends in Cell Biology:

NAD+ and sirtuins in aging and disease.


Restoring NAD+ by supplementing NAD+ intermediaries dramatically

ameliorates age-associated defects, counteracting many diseases of aging.

Cell Metabolism:

NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease.


NR supplementation led to marked improvement of certain mitochondrial disease in mice, and could potentially be successful in humans as well.

EMBO Molecular Medicine:

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3.


NR effectively delayed early- and late-stage mitochondrial disease progression in mice.

Cell Metabolism:

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.


NR supplementation in mammalian cells increases NAD+ levels, culminating in protection against hgh-fat diet-induced metabolic abnormalities.

Cognitive Function

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